Repurposing valproate for the treatment of colorectal cancer
Jump to navigation
Jump to search
 | We’re excited to announce the launch of the new STARDIT Version One at STARDIT.Wikimedia.org.au
All STARDIT reports (and our other material) from Wikispore have been imported to the new site — and any further editing or updating will take place there. The reports on Wikispore will be preserved as archived versions. The new version of this page can be accessed at: https://STARDIT.Wikimedia.org.au/wiki/Repurposing_valproate_for_the_treatment_of_colorectal_cancer |
Description: Colorectal cancer is a major cause of cancer related deaths for which there is an urgent need to develop new treatments. The drug valproate has been used to treat epilepsy and mood disorders for over 50 years. We have found that valproate can profoundly increase the anti-tumour activity of a class of drugs known as EGFR inhibitors in laboratory models of colon cancer. We will now test the activity of this drug combination in a phase II clinical trial in patients with advanced colon cancer.
Dates
State ongoing
Start 2021-01-01
End 2025-01-01
Form updated 2024-10-02
Report authors
Portia Dilena (link)
Location
Australia
URL
template:str right/Ga/Show/b9fca100-d6b6-44ee-9531-0855c69cbe98
Category
research